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本文对1970~1980年间 Vancouver 总医院15例结核性脑膜炎病人进行分析,其中9例脑脊液(CSF)培养牛结核杆菌阳性,2例呼吸道分离出该菌,1例尸检脑组织切片中见抗酸杆菌,其余根据临床及抗痨反应而诊断。15例中1/3死亡,存活中3例遗留神经系统后遗症。这些病人入院初被诊断为结核性脑膜炎3例,细菌性脑膜炎3例,脑脓肿2例,头痛2例,头或脊椎创伤2例,癫痫、发热、转移癌各1例。造成误诊的主要原因:①CSF 中含有大量多形
In this paper, 15 patients with tuberculous meningitis in the Vancouver General Hospital from 1970 to 1980 were analyzed. Nine of them were positive for M. tuberculosis cultured in cerebrospinal fluid (CSF), two were isolated from the respiratory tract and one was found in the autopsy brain tissue Bacillus, the rest based on clinical and anti-tuberculosis reaction diagnosis. One-third of 15 patients died and three survived neurological sequelae. At the beginning of admission, these patients were diagnosed as tuberculous meningitis in 3 cases, bacterial meningitis in 3 cases, brain abscess in 2 cases, headache in 2 cases, head or spine trauma in 2 cases, epilepsy, fever and metastatic carcinoma in 1 case. The main reason for misdiagnosis: ① CSF contains a large number of pleomorphic