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本文对40例经病理证实的胃肠道癌患者的血浆游离氨基酸谱和30例健康成人的血浆游离氨基酸谱进行了测定,对比。结果提示,患者组血浆游离氨基酸谱中有10项包括8项必须氨基酸下降,4项升高,必需氨基酸总和下降,支链氨基酸及其总量均下降,氨基酸总量下降。这些监测结果可作为胃肠道恶性肿瘤患者营养评价及辅助治疗的参考。
The plasma free amino acid profiles of 40 patients with pathologically confirmed gastrointestinal cancers and the plasma free amino acid profiles of 30 healthy adults were determined and compared. The results suggest that 10 of the patients’ plasma free amino acid profiles include 8 essential amino acid declines, 4 elevations, a decrease in the total number of essential amino acids, a decrease in branched-chain amino acids and total amounts, and a decrease in total amino acids. These monitoring results can be used as a reference for nutritional evaluation and adjuvant treatment of patients with gastrointestinal cancer.