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目的探讨非胰岛素依赖型糖尿病(NIDDM)患者的脂代谢异常及肌酸激酶(CK)变化的原因.方法检测病变组50例和对照组125例,空腹血糖(GLU)、空腹胰岛素(INS)、胆固醇(CH)、甘油三脂(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LI)L)、载脂蛋白AI(ApoAI)、载脂蛋白B(ApoB),并进行两者间均数比较.采用t检验.结果与正常对照组比较,NIDDM患者CK、ApoAI/ApoB、INS/GLU具显著性差异(P<0.001);TG、INS次之(P<0.01);CH、HDL、LDL、ApoAI、ApoB再次之(P<0.05).结论NIDDM患者可能因继发性胰岛素增高造成脂代谢紊乱及心肌损害.“,”Objective To find out the cause of abnormal lipid metaholism and CK changes in NIDDM. Methods Set up a patient group (50 subjects) and a control group(125 subjects),detect the fasting blood glucose,fasting blood insuliln,Chol,TG,HDL,LDL,ApoAI,A levels,and compare the averages between the two groups.Result The most significantly difference in CK.ApoAI/ApoB,insulin/hlood glucose levels was found hetween the two groups,next in TG,insulin (P