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对46例窦房结功能正常者(甲组)和36例病态窦房结综合征(SSS)患者(乙组)作食道心房调搏,分别测定其窦房传导时间(SACT)、窦房结恢复时间(SNRT)、校正的窦房结恢复时间(CSNRT)及高峰起搏周期(PCLp)。结果:SSS组的PCLp明显长于甲组(乙组为647±146ms, 甲组为539±127ms,P<0.001)。PCLp>600ms者,甲组占6例,乙组占22例,其差异呈高度显著性,P<0.005。将PCLp>600ms与CSNRT延长结合起来诊断SSS,可显著提高CSNRT的诊断敏感性,而不降低其诊断特异性及准确性。作者认为,PCLp>600ms可作为诊断SSS的新指标。
Forty-six patients with normal sinus node function (group A) and 36 patients with sick sinus syndrome (group B) underwent esophageal atrial pacing. The time of sinoatrial conduction (SACT) and sinoatrial node Recovery time (SNRT), corrected sinus node recovery time (CSNRT) and peak pacing cycle (PCLp). Results: PCLp in SSS group was significantly longer than that in group A (647 ± 146ms in group B, 539 ± 127ms in group A, P <0.001). PCLp> 600ms, group A accounted for 6 cases, group B accounted for 22 cases, the difference was highly significant, P <0.005. The combination of PCLp> 600 ms and CSNRT prolongation in the diagnosis of SSS can significantly improve the diagnostic sensitivity of CSNRT without diminishing its diagnostic specificity and accuracy. The authors believe that PCLp> 600ms can be used as a new indicator for the diagnosis of SSS.