论文部分内容阅读
在筛选抗丝虫药物的过程中,本文第2作者曾经发现左旋四咪唑对懒猴丝虫具有较高的作用。本文报告了该药治疗人体马来丝虫病的临床试验结果。观察是在马来西亚西部内格里森美兰地区马来丝虫病人中进行的。观察病例为3～72岁的男性和女性无症状微丝蚴血症病人,微丝蚴密度为1～30条/20立方毫米,采血于晚上八时进行,血片用吉氏液染色。所用剂量为成人单剂量3片;5～15岁儿童单剂2片;2～4岁儿童单剂1片,每片含左旋四咪唑盐酸盐40毫克,早饭后8点钟
In the screening of anti-filarial drugs, the second author of this paper once found that levamisole has a higher effect on the larval filarial worms. This article reports the results of a clinical trial of the drug in the treatment of human malaria. The observation was carried out among the malayian filariasis in Negri Melange, western Malaysia. The observed cases were asymptomatic microfilariae in 3-72-year-old men and women. Microfilaria density was 1 to 30/20 mm3. Blood samples were collected at 8:00 p.m., and blood films were stained with Kyrgyz liquid. The dose used for adult single dose of 3; 5 to 15-year-old children a single dose of 2; 2 to 4-year-old children a single dose of 1, each containing levamisole hydrochloride 40 mg, 8 o’clock after breakfast