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1 肝硬变概念的新认识 1826年Laennec首次提出“Cirrhosis”一词,意为橘黄色变硬的肝。后经Mollory(1911年)确认肝硬变的特点是肝实质破坏与纤维化。R(?)ssle(1930年)则在此基础上补充了肝实质再生。1956年,哈瓦那泛美胃肠病会议上曾为肝硬变确定了新标准:病变呈弥漫性,发展中有肝细胞坏死、再生结节、弥漫性肝纤维化、小叶中心带与汇管区有结缔组织束形成,肝小叶改建。1977年,世界卫生组织专题组又增补了血管系
1 new understanding of the concept of cirrhosis Laennec in 1826 for the first time proposed the word “Cirrhosis”, meaning orange hardened liver. After the Mollory (1911) confirmed cirrhosis is characterized by liver parenchymal destruction and fibrosis. R? Ssle (1930) supplemented liver parenchymal regeneration on this basis. In 1956, the Pan American gastroenterology conference in Havana set a new standard for cirrhosis: diffuse lesions with development of hepatocellular necrosis, regenerative nodules, diffuse hepatic fibrosis, centrilobular bands, and portal area Connective tissue bundle formation, hepatic lobule remodeling. In 1977, the WHO Task Team supplemented the vascular system