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作者在研究先吸入氟烷麻醉剂随后再吸入氯化钙或硫酸镁对被隔离的几内亚猪左心房肌肉的影响中,证明了一种自动测量肌肉收缩力的试管方法。采用自动计算机控制系统采集肌肉收缩力波形,并分析收缩波形来比较施药前和后的变化量。对于左心房肌肉,先分别施予二种浓度的氟烷(0.5和1.5％),过30分钟后再施予氯化钙或硫酸镁。从平均刺激—反应曲线中可自动检测出6种变量(潜伏期,到达张力峰值的时间,张力峰值,血压
The authors demonstrated a test-tube method for automatically measuring muscle contractility in a study of the effects of inhalation of a halothane anesthetic followed by calcium chloride or magnesium sulfate on isolated left atrial muscles of Guinea pigs. Automated computerized control system was used to collect the muscle contractility waveforms, and the contractile waveforms were analyzed to compare the changes before and after administration. For left atrial muscles, two concentrations of halothane (0.5 and 1.5%) were administered first and then calcium chloride or magnesium sulfate over 30 minutes later. Six variables (latency, peak time to peak, peak tension, blood pressure