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约2/3成人双相障碍(bipolar disorder,BD)患者首发于儿童期或青少年期,29%首发年龄早于13岁。儿童青少年BD(pediatric bipolar disorder,PBD)是指起病于18岁之前,以反复、交替发作的情感高涨和低落伴相应认知、行为改变为主要特征的一组重性精神障碍。发病年龄越小,意味着首次缓解后复发更早、情感正常的间歇期时间更
About two-thirds of adults with bipolar disorder (BD) are first episodes of childhood or adolescence, with 29% of first-onset patients being older than 13 years. Pediatric bipolar disorder (BD) refers to a group of severe mental disorders characterized by repetitive and alternating sentiments rising and falling with corresponding cognitive and behavioral changes before the onset of the disease. The younger age of onset means earlier relapse after the first remission, more frequent quiescence