论文部分内容阅读
为探讨膳食营养素与前列腺癌的关系,对102例前列腺癌患者进行了1∶1配比的病例对照研究。根据近三月食物摄入量的平均值计算蛋白质、脂肪、糖类等11种营养素及总执量的日平均摄入量,采用配对t检验和条件Logistic回归分析。结果表明:脂肪、糖类、视黄醇当量等的摄入量大能增加前列腺癌的危险性,维生素C、维生素B1等能降低其危险性,各营养素的多变量调整OR值及95%可信区间分别为脂肪1.65(1.39~1.96)、碳水化合物1.22(1.13~1.31)、视黄醇当量3.12(2.18~4.75)、维生素C0.61(0.46~0.80)、维生素B10.029(0.009~0.09)。本文还对各营养素增加或降低前列腺癌危险性的可能机制进行了讨论。
To investigate the relationship between dietary nutrients and prostate cancer, a case-control study of 102 patients with prostate cancer with a 1: 1 ratio was conducted. According to the average food intake in the past three months, the average daily intake of 11 nutrients, such as protein, fat, and carbohydrates, and the total volume of the products were calculated and analyzed by paired t-test and conditional Logistic regression. The results showed that the intake of fat, carbohydrate and retinol equivalent could greatly increase the risk of prostate cancer. Vitamin C and vitamin B1 could reduce their risk. The multivariate adjustment OR of each nutrient was 95% The confidence intervals were 1.65 (1.39-1.96), carbohydrates 1.22 (1.13-1.31) and retinal equivalents 3.12 (2.18-4.75), respectively, Vitamin C0.61 (0.46 ~ 0.80), Vitamin B10.029 (0.009 ~ 0.09). This article also discusses possible mechanisms by which nutrients may increase or decrease the risk of prostate cancer.