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目的比较异丙酚及联合硬膜外阻滞全麻诱导气管插管时的心肌氧供需平衡的变化。方法胸外科患者２２例（ＡＳＡ分级Ⅱ～Ⅲ级），随机分为异丙酚组（Ｐ组）和异丙酚联用硬膜外阻滞组（Ｅ组），用ＸＸＧ－Ｅ型心血管功能测定仪记录各项指标。结果两组病人应用异丙酚插管后平均动脉压和心脏指数未明显增高，Ｅ组总外周阻力和冠状动脉灌注压在硬膜外阻滞后和异丙酚诱导后均明显降低。插管后亦未提高，但Ｐ组总外周阻力在气管插管后增高；两组ＥＫＧ、心肌氧耗指数和心肌耗氧量在诱导插管前后均无明显变化，Ｅ组在硬膜外阻滞后及异丙酚诱导后下降，但在正常范围。结论异丙酚及联合硬膜外阻滞全麻诱导气管插管时对心肌氧供需平衡没有明显影响
Objective To compare the changes of myocardial oxygen supply and demand during tracheal intubation with propofol and epidural anesthesia. Methods Twenty-two patients with thoracic surgery (ASA grade Ⅱ ~ Ⅲ) were randomly divided into propofol group (P group) and propofol combined epidural block group (E group), with XXG-E type cardiovascular Function analyzer records various indicators. Results The mean arterial pressure and cardiac index were not significantly increased after propofol intubation in both groups. The total peripheral resistance and coronary perfusion pressure in group E were significantly lower after epidural block and after propofol induction. After intubation did not increase, but the total peripheral resistance in group P tracheal intubation increased; EKG, myocardial oxygen consumption index and myocardial oxygen consumption before and after induction of intubation had no significant change in group E in the epidural resistance Hysteresis and decrease after propofol induction, but in the normal range. Conclusion Propofol and combined epidural anesthesia induced tracheal intubation had no significant effect on myocardial oxygen supply and demand balance