ＡＳＰＡ是一个具有良好抗血栓作用的新药，本文观察了它对大鼠血 液流变性的影响，并于临床常用抗血小板药阿斯匹林同步进行了比较，在涉及到全 血、血细胞和血浆蛋白成分等九项流变学指标中，ＡＳＰＡ对其均有不同程度的作 用。其作用主要表现在该药能显著降低大鼠的全血粘度；使血沉加快、红细胞聚集 性降低，降低血小板粘附性，降低血浆纤维蛋白原含量等。实验结果表明，新药 ＡＳＰＡ具有多种血液流变学活性，且比阿斯匹林作用谱广，作用强度更大，有较大 的预防和治疗心血管疾病的潜力，值得进一步开发研究。 ASPA is a new anti-thrombotic drug. In this paper, the effect of aspirin on hemorheology in rats was observed and compared with aspirin, a commonly used antiplatelet drug in clinical practice. When it involves whole blood, blood cells and plasma proteins Composition and other nine rheological indicators, ASPA have different degrees of its role. Its main role in the drug can significantly reduce the viscosity of whole blood in rats; make erythrocyte sedimentation rate erythrocyte aggregation decreased, reduce platelet adhesion, reduce plasma fibrinogen content. Experimental results show that the new drug ASPA has a variety of hemorheological activity, and broader spectrum than aspirin, the role of intensity greater, greater potential for the prevention and treatment of cardiovascular disease, it is worth further study.