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目的：探讨顺序性四联免疫抑制方案在肾移植中的临床疗效。方法：对3例尸肾移植近期内使用骁悉（MMF）和短期小剂量ATG／CsA顺序性四联免疫抑制方案作为诱导免疫抑制方法观察肾功能恢复及急性排斥（AR）情况。结果：该3例术后第3d血肌酐均＜165μmol／L，说明移植肾功能恢复较快。术后对天内无出现AR、CsA肾中毒、感染等并发症。随防7mo－11mo，健康情况良好。结论：在肾移植功能即刻恢复者，预防性使用MMF、短期小剂量ATG／CsA顺序性四联方案可能是一种安全有效的免疫抑制方案。
Objective: To investigate the clinical efficacy of sequential quadruple immunosuppressive regimen in renal transplantation. Methods: Three cases of cadaveric renal transplantation (MMF) and short-term low-dose ATG / CsA sequential quadruple immunosuppression were used as immunosuppressive methods to observe the recovery of renal function and acute rejection (AR). Results: The three cases of postoperative third serum creatinine were <165μmol / L, indicating rapid recovery of renal function. No postoperative AR, CsA kidney poisoning, infection and other complications. With anti-7mo-11mo, good health. CONCLUSION: In the immediate recovery of renal function, preventive MMF and short-term, low-dose sequential ATG / CsA regimen may be a safe and effective immunosuppressive regimen.