[目的]分析浙江省肿瘤登记地区2000~2009年胃癌发病与死亡的流行状况。[方法]2000~2009年胃癌发病与死亡数据来源于浙江省6个肿瘤登记地区,分析性别、年龄别胃癌发病死亡率。人口标化率采用全国1982年标准人口构成结构和Segi’s世界标准人口结构。[结果]2000~2009年浙江省肿瘤登记地区胃癌发病率为30.88/10万。发病率从2000年的23.02/10万升高至2009年的38.54/10万,年度变化百分比(APC)为4.39%(95%CI:1.92~6.91)。2000~2009年浙江省肿瘤登记地区胃癌死亡率为22.81/10万,死亡率呈现小幅度上升趋势,APC=4.95%(95%CI:2.76~7.19)。胃癌发病与死亡在55岁之后呈现明显增长趋势,发病在75~79岁组达到高峰,死亡在80~84岁组达到高峰。[结论]应加强防癌知识宣传,建议将40岁以上人群作为浙江省开展胃癌早诊早治的重点对象。 [Objective] To analyze the prevalence of gastric cancer incidence and death from 2000 to 2009 in Zhejiang province’s tumor registration area. [Methods] The incidence and mortality of gastric cancer from 2000 to 2009 were collected from 6 cancer registration areas in Zhejiang Province. The incidence of gastric cancer was analyzed. The standardization rate of population adopts the standard population structure of China in 1982 and Segi’s world standard population structure. [Results] The incidence of gastric cancer in Zhejiang Cancer Registration Area from 2000 to 2009 was 30.88 / 100000. The incidence increased from 23.02 / 100,000 in 2000 to 38.54 / 100,000 in 2009, with an annual percentage change (APC) of 4.39% (95% CI: 1.92-6.91). The incidence of gastric cancer was 22.81 / 100 000 in Zhejiang Cancer Registry Area from 2000 to 2009, with a slight upward trend in mortality rate, APC = 4.95% (95% CI: 2.76-7.19). The incidence of gastric cancer and death after 55 years of age showed a clear trend of growth, the incidence peaked in the 75-79 year-old group, death in the 80-84 year-old group reached its peak. [Conclusion] The propaganda of anti-cancer knowledge should be strengthened. It is suggested that people over 40 years old should be regarded as the key target for early diagnosis and treatment of gastric cancer in Zhejiang Province.