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本文测定了22例肾小球疾病患儿血及尿中可溶性白细胞介素2受体(sIL-2R)含量,结果显示疾病组急性期血及尿液sIL-2R明显高于对照组(P<0.01),且血与尿液sIL-2R含量有明显相关性(P<0.01),恢复期sIL-2R显著下降,与急性期相比有显著意义(P<0.01)。提示sIL-2R为评价肾小球疾病免疫失衡的一项重要临床参考指标。
In this study, the serum and urine soluble interleukin 2 receptor (sIL-2R) levels were measured in 22 children with glomerular disease. The results showed that sIL-2R levels in acute stage of the disease group were significantly higher than those in the control group (P < 0.01). There was a significant correlation between blood and urine sIL-2R content (P <0.01) and sIL-2R at convalescent stage (P <0.01). It is suggested that sIL-2R is an important clinical reference for evaluating immune imbalance of glomerular diseases.