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本文作者对1985年1月至1994年2月间手术切除的23例直径<3cm的小肝癌的临床病理特点进行了分析。23例病人中,有明显肝癌包膜者13例(56.5%)。术后1年、3年、5年生存率分别为91.3%、79.1%、67.8%,预后明显优于一般肝癌手术切除者。结果表明,小肝癌的生物学特性与晚期肝癌有所不同,直径<3cm的小肝癌处于相对良性状态,预后较好。为了改善肝癌的预后,早期诊断小肝癌十分重要。作者还对<3cm小肝癌的血清AFP浓度及病理特点等进行了讨论。
The authors analyzed the clinicopathological features of 23 cases of small hepatocellular carcinoma with a diameter of <3cm between January 1985 and February 1994. Of the 23 patients, 13 (56.5%) had liver cancer capsules. The 1-year, 3-year, and 5-year survival rates were 91.3%, 79.1%, and 67.8%, respectively. The prognosis was significantly better than that of patients undergoing liver cancer resection. The results show that the biological characteristics of small hepatocellular carcinoma are different from those of advanced hepatocellular carcinoma. Small hepatocellular carcinoma with a diameter of <3 cm is in a relatively benign state with a good prognosis. In order to improve the prognosis of liver cancer, early diagnosis of small liver cancer is very important. The authors also discussed the serum AFP concentration and pathological features of <3cm small hepatocellular carcinoma.