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目的 探讨高血压病和糖尿病患者早期肾脏损害的灵敏检测方法。方法 患者血 β２Ｍ 及尿液 β２Ｍ ，Ａｌｂ，ＩｇＧ 放免测定值与正常对照组测定值进行比较。结果 经过放免检测及统计学处理，高血压病和糖尿病血β２Ｍ 及尿β２Ｍ ，Ａｌｂ，ＩｇＧ 测定水平均高于正常对照组（Ｐ＜ ０．０１）。结论 血清 β２Ｍ 和尿液β２Ｍ ，Ａｌｂ，ＩｇＧ 放免测定是了解高血压病和糖尿病患者早期肾脏损害的灵敏方法。
Objective To explore sensitive detection of early renal damage in hypertensive and diabetic patients. Methods The levels of β2M and β2M, Alb and IgG in blood of patients were compared with those of the normal control group. Results After radioimmunoassay and statistical analysis, β2M and β2M, Alb and IgG levels in patients with hypertension and diabetes mellitus were higher than those in the normal control group (P <0.01). Conclusion Serum β2M and urine β2M, Alb, IgG radioimmunoassay is a sensitive method to understand the early renal damage in hypertensive and diabetic patients.