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以前,自然流产的原因从理论上分为母体方面和胎儿方面,或者属于子宫排出胎儿的机制。后者则与胎芽、胎儿死亡有关,很久以前就推测染色体异常及遗传障碍是自然流产的原因之一。1961年开始有自然流产染色体异常的报告,现已认为染色体异常是流产的最大原因。一、自然流产中染色体异常的频率本教研室在过去七年共收集自然流产物1,115例。其中确定为胎儿方面的组织而采用者为900例,进行染色体分析者583例,结果发现284例(48.7%)染色体异常。关于自然流产儿的染色体异常率,WHO1966年公布为19.4%(在综合各资料788例中占153例),此值长期被引用。并误释
In the past, the causes of spontaneous abortion theoretically divided into maternal and fetal aspects, or belonging to the uterus to discharge the fetus mechanism. The latter is associated with fetal death and fetal death. It was speculated long ago that chromosomal abnormalities and genetic disorders are one of the causes of spontaneous abortion. A report of chromosomal abnormalities in spontaneous abortion began in 1961 and chromosomal abnormalities have now been identified as the leading cause of miscarriage. First, the frequency of chromosomal abnormalities in spontaneous abortion The Department in the past seven years collected a total of 1,115 cases of natural flow products. Of these, 900 were identified as fetal tissues and 583 were analyzed by chromosomal analysis. As a result, 284 (48.7%) chromosomal abnormalities were found. Regarding the rate of chromosomal abnormalities in spontaneous abortion, the WHO published 19.4% in 1966 (153 out of 788 cases in the combined data), a long-term reference. And mistakenly explained