目的:了解医源性早产对母婴预后的影响,并探讨掌握适时终止妊娠的时机,降低医源性早产发生。方法:对该院2005年1～12月分娩的早产病例分成医源性早产组、自发性早产组和胎膜早破早产组进行总结分析。结果:2005年全年分娩早产病例472例,其中医源性早产233例,占早产的49.36%,自发性早产组和胎膜早破早产组分别为22.25%、28.39%。医源性早产的新生儿窒息率为20.17%,无围产儿死亡;自发性早产组和胎膜早破早产组为49.52%和35.07%,围产儿死亡率为8.57%和6.72%。医源性早产的前3位原因分别是胎儿宫内窘迫、妊娠肝内胆汁淤积症和胎膜早破,而<34周医源性早产原因依次为胎膜早破、子痫前期重度、妊娠肝内胆汁淤积症和胎儿宫内窘迫。医源性早产剖宫产率为100%,自发性早产组和胎膜早破早产组分别为9.52%和11.94%。结论:医源性早产在早产中的比例为49.36%,医源性早产围产儿近期质量明显优于自发性早产组和胎膜早破早产组。重视医源性早产原因的预防及提高正确的处理方式可以降低医源性早产儿的出生。 Objective: To understand the impact of iatrogenic preterm labor on the prognosis of maternal and infant, and explore the timing of timely termination of pregnancy and reduce the incidence of iatrogenic preterm birth. Methods: The hospitalized cases of premature labor from January to December in 2005 were divided into iatrogenic preterm group, spontaneous preterm group and premature rupture of membranes group. Results: In the whole year of 2005, there were 472 cases of premature delivery of childbirth, including 233 cases of iatrogenic preterm birth, accounting for 49.36% of preterm birth and 22.25% and 28.39% of preterm preterm birth group and premature rupture of membranes group respectively. Neonatal asphyxia in iatrogenic preterm birth was 20.17%, with no perinatal death; spontaneous preterm birth group and premature rupture of membranes group was 49.52% and 35.07%, perinatal mortality rate was 8.57% and 6.72%. The first three causes of iatrogenic preterm birth were fetal distress, intrahepatic cholestasis of pregnancy and premature rupture of membranes, respectively. The causes of iatrogenic preterm birth in 34 weeks were as follows: premature rupture of membranes, severe preeclampsia, intrahepatic pregnancy Cholestasis and Fetal Distress. Iatrogenic cesarean section rate was 100%, spontaneous premature rupture of membranes group and premature rupture of 9.52% and 11.94% respectively. Conclusion: The proportion of iatrogenic preterm birth in preterm labor is 49.36%. The recent quality of perinatal preterm birth is obviously better than those in spontaneous premature labor and premature rupture of membranes. Pay attention to the prevention of iatrogenic premature causes and improve the correct treatment can reduce the birth of iatrogenic premature children.