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一向认为硷性反流性胃炎是由于十二指肠内容物反流所致,转流手术是唯一有效的治疗方法。但是晚近发现,约有30~50%的病人手术后症状未能改善。主要的困难是本病尚缺乏正确的诊断方法,内窥镜检查及胃粘膜活检均未能发现胃粘膜病变与病人症状之间存在相关联系。作者受到Bernstein用盐酸滴入食管来诊断反流性食管炎的启示,创用胃内硷灌注试验作为诊断本病的新方法。试验对象共56例,分为三组:第一组:21例,证实为硷性反流性胃炎。均经胃镜检查,见有胃内胆汁反流,粘膜染有胆汁及吻合口周围糜烂和水肿。粘膜活检有不同程度的炎症改变。第二组:18例,均无上腹部活动性疾病或症状,作为正常对照。第三组:17例,除外
Alkaline reflux gastritis has always been thought to be due to reflux of duodenal contents, and bypass surgery is the only effective treatment. But recently found that about 30 to 50% of patients failed to improve after surgery symptoms. The main difficulty is the lack of proper diagnosis of this disease, endoscopy and gastric biopsy failed to find the gastric mucosal lesions and the relationship between the patient’s symptoms. The authors received Bernstein hydrochloric acid drip into the esophagus to diagnose reflux esophagitis enlightenment, the use of gastric perfusion test as a new method of diagnosis of the disease. A total of 56 subjects were divided into three groups: the first group: 21 cases, confirmed as alkaline reflux gastritis. Have gastroscopy, see the stomach bile reflux, mucosa stained with bile and anastomosis around the erosion and edema. Mucosal biopsy has varying degrees of inflammatory changes. The second group: 18 cases, no upper abdominal active disease or symptoms, as a normal control. The third group: 17 cases, except