THE CHANGES OF IL-1β AND IL-6 LEVEL AT DIFFERENT ALTITUDE AND THEIR SIGNIFICANCE

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Objective To investigate the changes of the concentration of interkeukine β 1(IL-1β) and Interleukine 6(IL-6) in the serum of the people who live in the different altitude,and try to find the relation between the cytokines(CK) and the hypoxia adaptation and some diseases caused by hypoxia.Methods Using enzyme linked immunoabsorbent assay(ELISA) to detect the level of the concentration of IL-1β and IL-6 in the serum.Results The concentration of IL-1β showed significant increase in values(P<0.05) at 4050m.IL-6 in same altitude showed obvious changes as well(P<0.05).Conclusion The results showed that the concentration of IL-1β and IL-6 have significant changes in the serum.This means that they may be involved in the process of the adaptation and some sickness because of hypoxia. Objective To investigate the changes of the concentration of interkeukine β 1 (IL-1β) and Interleukine 6 (IL-6) in the serum of the people who live in the different altitude, and try to find the relation between the cytokines (CK) and the hypoxia adaptation and some diseases caused by hypoxia. Methods Using enzyme linked immunoabsorbent assay (ELISA) to detect the level of the concentration of IL-1β and IL-6 in the serum. Results The concentration of IL-1β showed significant increase in The results showed that the concentration of IL-1β and IL-6 have significant changes in the serum. This means that they may be involved in the process of the adaptation and some sickness because of hypoxia.
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