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目的探讨老年Ⅱ型糖尿病患者的糖尿病视网膜病变与血流变紊乱 的关系。方法对DR组27例、无DR组24例以及正常对照组25例进行血流变指标 和血脂的检测。结果 糖尿病组的全血粘度、血浆粘度、纤维蛋白原、红细胞聚集指 标、甘油三脂和总胆固醇明显高于正常对照组,红细胞变形指数低于正常对照组, 这些变化在 DR组更显著(p<0.01)。提示血流变紊乱与老年Ⅱ型 DM患者 DR的 发生发展有密切关系,及时和长期控制高血粮、高脂血症,降低血液粘度对防治老 年病人 DR有重要的临床意义。
Objective To investigate the relationship between diabetic retinopathy and disorder of blood rheology in elderly type Ⅱ diabetic patients. Methods 27 cases of DR group, 24 cases without DR group and 25 cases of normal control group, the indexes of hemorheology and blood lipid were detected. Results The whole blood viscosity, plasma viscosity, fibrinogen, erythrocyte aggregation index, triglyceride and total cholesterol in diabetic group were significantly higher than those in normal control group, and the index of erythrocyte deformability was lower than that in normal control group. These changes were more significant in DR group (p <0.01). It is suggested that there is a close relationship between the disturbance of blood rheology and the occurrence and development of DR in elderly type-II DM patients. It is of great clinical significance to control long-term high and high blood lipid, hyperlipidemia and blood viscosity in the prevention and treatment of DR in elderly patients.