本文应用体外培养人淋巴细胞和小鼠骨髓细胞微核的检测，对低剂量γ射线与香烟的复合诱变作用进行了研究。结果表明：香烟（０８～１支／ｍｌ）与低剂量γ射线（０．２５１０Ｇｙ）均显著诱发培养人淋巴细胞微核的形成（Ｐ＜００１），并呈明显的剂量效应；低剂量γ射线联合香烟处理培养人淋巴细胞，诱发微核率显著高于对照组。小鼠体内实验也表明了低剂γ射线联合高浓度香烟对小鼠骨髓细胞微核有明显诱发作用。结果提示低剂量γ射线联合香烟可加强遗传物质的损伤 In this study, we detected the micronuclei of human lymphocytes and mouse bone marrow cells in vitro and studied the mutagenic effects of low-dose γ-rays and cigarette. The results showed that the formation of micronuclei in human lymphocytes was significantly induced by cigarette (08-1 / ml) and low dose γ-ray (0.2510Gy) Dose effect; low-dose γ-ray combined with cigarette culture of human lymphocytes, induced micronucleus rate was significantly higher than the control group. In vivo experiments in mice also showed that low-dose γ-rays combined with high concentrations of cigarettes on mouse bone marrow micronucleus significantly induced. The results suggest that low-dose γ-rays combined with cigarettes can enhance the genetic material damage