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目的观察隆突性皮肤纤维肉瘤(DFSP)的临床病理特点。方法对10例病例进行临床表现、组织形态学、免疫组化分析。结果 10例好发中青年男性,肿瘤单发或多发性结节,位于真皮,可浸润皮下脂肪组织。组织形态除经典的车辐状或席纹状结构外,还存在一些变异,如黏液变性,伴纤维肉瘤区域等。10例DFSP 8例CD34阳性,2例灶状阳性。结论掌握DFSP的临床病理特点,避免与其他皮肤梭形细胞肿瘤混淆。
Objective To observe the clinicopathological features of dermatofibrosarcoma (DFSP). Methods The clinical manifestations, histomorphology and immunohistochemistry of 10 cases were analyzed. Results Ten cases of middle-aged and young men, single or multiple tumor nodules, located in the dermis, subcutaneous adipose tissue can be infiltrated. Tissue morphology in addition to the classic car spokes or stripes structure, there are still some variations, such as mucinous degeneration, with fibrosarcoma area. 10 cases of DFSP 8 cases of CD34 positive, 2 cases of positive staining. Conclusions Grasp the clinical and pathological features of DFSP to avoid confusion with other skin spindle tumors.