纤维上皮瘤原属卵巢肿瘤,近年有报告发生于睾丸旁及性腺外者。经电镜观察,其组织发生目前倾向来源于体腔上皮或尿路上皮。本瘤是否有内分泌反应,文献久有争论,目前积累资料证实肿瘤可产生内分泌素,并将其分为增生、良性及恶性。 历史回顾 本瘤于1898年首先以腺纤维瘤样瘤命名报告。一年后,有称其为表浅乳头状癌性纤维瘤。Bren-ner(1907)称其为滤泡性卵巢瘤并详细报道3例,直至Meyer(1932)命名为勃勒纳氏瘤。国内统一命名(1974)为纤维上皮瘤。 组织来源 多年来意见分歧,迄今尚未统一认识。 粒层细胞来源:Brenner(1907)~2提出本瘤来源于成熟卵泡的粒层细胞,后由Teoh(1953)~3所 Fibroepithelioma is an ovarian tumor, in recent years there have been reports of parathyroid and gonadal outside. Observed by electron microscopy, the current occurrence of its tissue derived from the body cavity epithelium or urinary tract epithelium. The tumor is endocrine reaction, the literature has long been controversial, the current accumulation of data confirm that the tumor can produce endocrine and divided into hyperplasia, benign and malignant. History review The tumor was first reported in 1898 named adenomatous tumor. A year later, it was called superficial papillary cancerous fibroids. Bren-ner (1907) called follicular ovarian tumor and reported 3 cases in detail until Meyer (1932) was named Brenner’s tumor. The domestic name (1974) for the fibrous epithelial tumor. The disagreements over the sources of the organization’s sources over the years have not yet been unanimously recognized. Granulosa cells Source: Brenner (1907) ~ 2 proposed the tumor derived from mature follicles granulosa cells, followed by Teoh (1953) ~ 3