论文部分内容阅读
目的观察幽门螺杆菌 (Hp)与胃及十二指肠粘膜病理组织学表现之间的关系。方法对 6 0例慢性胃炎和 2 2例十二指肠溃疡患者经胃镜分别从胃窦、胃体、十二肠球部取活检 ,进行组织学检测。结果在活动性胃炎中无论是胃窦部或胃体部 Hp检出率近 10 0 % ,显著高于活动性十二指肠球炎的球部 Hp的检出率。胃窦部 Hp总检出率及活动性炎症的发生率均显著高于胃体部及十二指肠球部。2 2例十二指肠球部溃疡 Hp在球部的检出率为 5 4% ,显著低于其在胃窦部组织中 Hp10 0 %的检出率。结论 Hp感染是胃粘膜活动性炎症的重要原因 ,并以此为基础发展为重度粘膜炎及溃疡病 ,因此 ,对某些慢性胃炎患者应及早进行 Hp根除治疗
Objective To observe the relationship between Helicobacter pylori (Hp) and gastric and duodenal mucosa histopathology. Methods Sixty patients with chronic gastritis and 22 patients with duodenal ulcer were biopsied from the gastric antrum, corpus, and duodenum respectively by gastroscopy for histological examination. Results In active gastritis, the detection rate of Hp in gastric antrum or gastric body was almost 100%, which was significantly higher than that in active duodenal inflammation. The detection rate of Hp in gastric antrum and the incidence of active inflammation were significantly higher than those in gastric body and duodenal bulb. The detection rate of Hp in the duodenal ulcer was 54% in 2 cases, which was significantly lower than that of Hp10 0% in gastric antrum. Conclusion Hp infection is an important cause of active gastric mucosal inflammation, and as a basis for the development of severe mucositis and ulcer disease, therefore, some patients with chronic gastritis should be treated early Hp eradication