尘肺病是在长期职业活动中吸入生产性粉尘并在肺内潴留而引起的以肺组织弥漫性纤维化为主的全身性疾病。尘肺患者巨噬细胞破坏,感染肺结核的概率明显高于普通人群。尘肺合并肺结核后,可加速尘肺结节融合和肺纤维化,肺功能减退;而尘肺又可加重肺结核,二者相互促进,促使病情恶化,影响预后,增加病死率。尘肺合并肺结核痰菌阳性率低,按痰检抗酸杆菌金标准易造成漏诊或延误诊断,寻找快速诊断方法势在必行。近年来利用 Pneumoconiosis is a systemic disease characterized mainly by diffuse fibrosis of the lungs caused by the inhalation of productive dust in long-term occupational activities and retention in the lungs. Macrophage destruction of pneumoconiosis patients, the probability of tuberculosis was significantly higher than the general population. Pneumoconiosis combined with pulmonary tuberculosis can accelerate the fusion of pneumoconiosis and pulmonary fibrosis, pulmonary dysfunction; and pneumoconiosis can aggravate tuberculosis, the two promote each other, prompting the deterioration of the condition, affect the prognosis and increase mortality. Pneumoconiosis with tuberculosis sputum positive rate is low, according to sputum acid-fast bacilli gold standard easily lead to missed diagnosis or delay diagnosis, looking for a rapid diagnostic method is imperative. In recent years