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目的:探讨黏膜下剥离术(ESD)治疗早期消化道肿瘤的临床效果和安全性方法:回顾性分析2010年3月至2014年6月我院收治的48例早期消化道肿瘤患者的临床病历资料,根据治疗方法不同分为ESI)纽和外科组观察比较两组患者的治愈性切除率、出血情况、穿孔情况、手术时间、术后胃肠功能恢复时间、住院费用及住院时间结果:ESD组25例,外科组23例,均顺利完成手术ESD与外科手术相比,在治愈性切除率(23/25,92.0%vs 21/23,91.3%)、手术时间(117.4±25.7 min vs 133.9±31.2 min)、出血及穿孔并发症(2/25,8.0%vs 3/23,13.0%)方面差异无统计学意义(P>0.05),而术后胃肠功能恢复时间短(2.2±0.9d vs 4.1±0.9d),住院费用较少(16 609.0±409.9元vs 25 526.1±369.5元),住院时间短(6.6±1.7 d vs 10±1.6d),差异有统计学意义(P<0.05)结论:在消化道早期肿瘤的治疗方面,ESD与外科手术疗效相当,但ESD较外科手术创伤小、住院时间短、住院费用少且术后恢复快,可以作为首选方法
Objective: To investigate the clinical efficacy and safety of submucosal dissection (ESD) in the treatment of early gastrointestinal tumors.Methods: The clinical records of 48 patients with early gastrointestinal cancer who were treated in our hospital from March 2010 to June 2014 were retrospectively analyzed. , According to the different treatment methods were divided into ESI) New Zealand and the surgical group were observed and compared the curative resection rate, bleeding, perforation, operation time, postoperative gastrointestinal function recovery time, hospitalization costs and length of stay Results: ESD group 25 cases, and 23 cases in surgical group. All patients underwent surgery successfully. Compared with surgical resection, the resection rate (23/25, 92.0% vs 21 / 23,91.3%), operation time (117.4 ± 25.7 min vs 133.9 ± 31.2 min), hemorrhage and perforation complications (2 / 25,8.0% vs 3 / 23,13.0%), but there was no significant difference between the two groups (P> 0.05) vs 4.1 ± 0.9d), less hospitalization expense (16 609.0 ± 409.9 yuan vs 25 526.1 ± 369.5 yuan), shorter hospital stay (6.6 ± 1.7 days vs 10 ± 1.6 days), the difference was statistically significant (P0.05) Conclusion: In the treatment of early digestive tract tumors, ESD is equivalent to surgery, but ESD is less invasive than surgery and shorter in hospital stay, Less hospital costs and rapid recovery can be used as the preferred method