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目的探讨根除幽门螺杆菌(Hp)治疗,对于Hp阳性功能性消化不良(FD)飞行员患者的临床疗效和复发情况。方法将64例FD患者随机分为治疗组和对照组,分别给予奥美拉唑+阿莫西林+甲硝唑和奥美拉唑+多潘立酮治疗。疗程均为2周。治疗结束后4周胃镜复查和Hp检测。1年后随访。结果治疗后两组症状积分均显著降低(P<0.01)。1年后治疗组症状积分明显低于对照组(P<0.05)。结论在从军事效益—费用—疗效比方面看,短疗程根除Hp是治疗Hp阳性FD飞行员患者的优势方案。
Objective To investigate the clinical efficacy and recurrence of Helicobacter pylori (Hp) treatment in patients with Hp positive functional dyspepsia (FD). Methods Sixty-four FD patients were randomly divided into treatment group and control group, and were given omeprazole, amoxicillin, metronidazole and omeprazole plus domperidone respectively. The course of treatment is 2 weeks. Gastroscopy and Hp testing 4 weeks after treatment. Follow-up after 1 year. Results After treatment, symptom scores of both groups were significantly decreased (P <0.01). One year later, the symptom score of the treatment group was significantly lower than that of the control group (P <0.05). Conclusions From a military benefit-cost-efficacy perspective, short-course eradication of Hp is an advantage for the treatment of patients with Hp-positive FD pilots.