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在临床上诊断为细菌性心内膜炎的病例中,约15%未能检出致病菌。对于这种“阴性”血培养曾提出过许多可能的原因,包括这种卫星链球菌(即在血琼脂上仅能在其它细菌菌落周围生长的营养缺陷菌)在实验室常规条件下不能生长,而仅在培养基偶尔被污染后才发现其存在。已有报告卫星链球菌能引起心内膜炎,但在文献及实践中未能引起注意。 1975至1977三年间,Baltimore的Sinai医院共收治了20名细菌性心内膜炎患者,其中有下列3例是由卫星链球菌引起的(15%):例1是一个患有先天性风疹综合征、唇腭裂、无紫绀性法罗氏四联症的11岁男孩。77年5月因发展有嗜睡、头痛及发烧而住院。在3周时间里进行了16次血培养皆为阴性,
About 15% of clinically diagnosed cases of bacterial endocarditis failed to detect pathogens. Many possible reasons for this “negative” blood culture have been raised, including the fact that this S. hyopneumoniae, an auxotrophic bacterium that grows only around other bacterial colonies on blood agar, can not grow under routine laboratory conditions, It is found only after the culture medium is contaminated occasionally. It has been reported that S. gonorrhoeae can cause endocarditis but failed to draw attention in the literature and in practice. Between 1975 and 1977, 20 patients with bacterial endocarditis were admitted to the Sinai Hospital in Baltimore. The following 3 cases were caused by S. sotali (15%): Case 1 was a case of congenital rubella syndrome Levy, cleft lip and palate, non-cyanotic tetralogy of Fallot 11-year-old boy. May 77 due to the development of lethargy, headache and fever and hospitalization. 16 blood cultures were negative in 3 weeks,