低血糖后的高血糖反应称为 Somogyi 现象,以往认为是因拮抗激素分泌过多和胰岛素缺乏共同所致。近来发现该种现象的发生并非必须有胰岛素缺乏,而拮抗激素起着主要作用。以前的研究表明,在胰岛素诱发的低血糖反应中,胰岛糖素、肾上腺素、皮质醇和生长激素分泌增多,但各种激素所起的作用尚未肯定。本实验研究了胰岛素依赖型糖球病(IDDM)病人在接受生长抑素-胰岛素-葡萄糖输入试验(SIGIT)时,生长激素(GH)和皮质醇对血糖水平的影响。 Hyperglycemia after hypoglycemia is called the Somogyi phenomenon, previously thought to be due to antagonism of excessive hormone secretion and insulin deficiency. Recently found that the occurrence of this phenomenon does not have to have insulin deficiency, and antagonist hormones play a major role. Previous studies have shown that in the insulin-induced hypoglycemic response, insulin secretion, epinephrine, cortisol and growth hormone secretion increased, but the role of various hormones has not been affirmed. This study examined the effects of growth hormone (GH) and cortisol on blood glucose levels in patients with insulin-dependent glycomedopathy (IDDM) receiving the somatostatin-insulin-glucose infusion trial (SIGIT).