论文部分内容阅读
目的：探讨小儿应用地塞米松前后对 Ｔ 细胞的影响。方法：在患儿应用地塞米松前后分别抽取空腹血行 Ｔ 细胞亚群检测（ Ｍ Ｃ Ａ Ｂ Ａ Ｅ 花环法），分析其与用药前后、用药次数、患儿年龄、疾病种类的关系。结果： Ｔ 细胞亚群在正常组与用药前间无显著性差异（ Ｐ＞ ００５），而正常组和用药前与用药后、用药次数、疾病种类间均有显著性差异（ Ｐ＜ ００５）。结论：地塞米松对小儿外周血 Ｔ 细胞有明显影响，临床医生在应用地塞米松前应考虑到对免疫功能的影响。
Objective: To investigate the effect of dexamethasone on T cells in pediatric patients. Methods: Before and after dexamethasone treatment in children, fasting blood T lymphocyte subsets were detected (M C A BA E rosette method), and their relationship with medication frequency, number of children, age of children and disease types were analyzed. Results: There was no significant difference in T cell subsets between the normal group and before treatment (P> 005), but there were significant differences between the normal group and before treatment and after treatment 05). Conclusion: Dexamethasone has a significant effect on T cells in pediatric patients. Clinicians should consider the influence on immune function before dexamethasone application.