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目的 :探讨系统性红斑狼疮 (SLE)患者红细胞Ⅰ型补体受体 (ECR1)密度相关基因多态性分布与SLE患者临床表型间的相关性 .方法 :采用聚合酶链式反应(PCR )结合HindⅢ内切酶限制性片段长度多态性(RFLP)技术对 5 8例SLE患者的ECR1密度相关基因多态性分布进行测定 ,并比较不同基因型
Objective: To investigate the correlation between the distribution of erythrocytic type 1 complement receptor (ECR1) density-related gene polymorphism and clinical phenotype in patients with systemic lupus erythematosus (SLE) .Methods: Polymerase chain reaction (PCR) Hind Ⅲ endonuclease restriction fragment length polymorphism (RFLP) technique was used to determine the distribution of ECR1 density-related gene polymorphisms in 58 SLE patients and to compare the genotypes of different genotypes