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目的探讨特布他林联合布地奈德雾化吸入治疗慢性支气管炎急性发作期的临床疗效及安全性。方法采用随机分组法将60例慢性支气管炎急性发作期患者分为治疗组和对照组。对照组给予常规治疗(抗生素、氨茶碱、氨溴索及营养支持等治疗),治疗组加用特布他林联合布地奈德通过氧驱动雾化吸入治疗,一周后进行疗效评定。结果治疗组与对照组总有效率比较差异有显著意义(P<0.05),治疗组疗效明显优于对照组。结论特布他林联合布地奈德雾化吸入治疗慢性支气管炎急性发作期安全有效,值得临床推广应用。
Objective To investigate the clinical efficacy and safety of terbutaline combined with budesonide inhalation in the treatment of acute exacerbation of chronic bronchitis. Methods Sixty patients with acute exacerbation of chronic bronchitis were randomly divided into treatment group and control group. The control group was given routine treatment (antibiotics, aminophylline, ambroxol and nutritional support and other treatment), the treatment group plus terbutaline combined with budesonide inhaled by oxygen inhalation therapy, a week after the curative effect evaluation. Results The total effective rate of the treatment group and the control group was significantly different (P <0.05), the treatment group was significantly better than the control group. Conclusion Terbutaline combined with budesonide inhalation is safe and effective in the treatment of acute exacerbation of chronic bronchitis, which is worthy of clinical application.