目的:通过药效学实验,比较出临床上常用的四种复方中药对脾胃虚寒实验大鼠的影响。方法:紫外分光光度法测定大鼠酚红胃排空率,胃重指数,酶联免疫法测定血清胃泌素(GAS)、胃动素(MTL)指标变化。结果:均与模型对照组比较,良附丸和附子理中汤组对胃酚红排空率有统计学意义。附子理中汤组对GAS、MTL有统计学意义,良附丸组对MTL有以及小建中汤组对GAS有统计学意义。结论:附子理中汤对此模型脾胃虚寒大鼠的治疗作用明显。 OBJECTIVE: To compare the effects of four kinds of traditional Chinese herbs commonly used clinically on rats with spleen and stomach deficiency syndrome through pharmacodynamic experiments. Methods: UV-Vis spectrophotometry was used to determine the gastric emptying rate and gastric mass index. Serum gastrin (GAS) and motilin (MTL) levels were measured by enzyme-linked immunosorbent assay. Results: Compared with the model control group, the gastric perfusion rate of gastric ulcer was significantly higher in Liangfu pill and Fuzi Li Zhong Tang group. Aconite in the soup group of GAS, MTL was statistically significant, Liang Fu pill MTL group and Xiaojianzhong decoction of GAS was statistically significant. Conclusion: Fuzi Lizhong Decoction has a significant therapeutic effect on this model of spleen and stomach Deficiency in rats.