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目的分析高危妊娠11~14周胎儿超声筛查的意义。方法选择1 000例11~14孕周胎儿作为研究对象,分析超声检查结果,并对胎儿妊娠结果进行随访。结果本次共发现畸形胎儿150例,占15.00%,其中以NT增厚、颈部水囊瘤、双胎特有畸形检出率最高(100.00%),其次为神经系统畸形与骨骼四肢畸形检出率分别为95.00%与83.87%,泌尿系统畸形率为75.00%,未检出消化系统畸形与呼吸系统畸形。150例结构畸形胎儿中19例(12.67%)随访正常,47例(31.33%)胎儿家属同意被引产,其余84例(56.00%)为正常生产。超声诊断结果与引产或胎儿出生情况基本一致。本次超声筛查敏感性为87.33%(131/151),特异性为100.00%(150/150),阳性预测值为100.00%(150/150)。结论对高危妊娠胎儿进行早期超声诊断筛查畸形具有重要意义,有效预防不良妊娠结局的发生。
Objective To analyze the significance of fetal ultrasound screening in 11-14 weeks of high risk pregnancy. Methods A total of 1 000 fetuses of 11-14 gestational weeks were selected as the study objects. The results of ultrasound examination were analyzed and the results of fetus pregnancy were followed up. Results A total of 150 malformation fetuses were found, accounting for 15.00%. Among them, NT was the most common type of neck fetus with the highest percentage of abnormalities (100.00%), followed by nervous system abnormalities and skeletal limb deformities Rates were 95.00% and 83.87%, urinary system malformation rate was 75.00%, did not detect digestive system deformities and respiratory malformations. Of the 150 malformation fetuses, 19 (12.67%) had normal follow-up, 47 (31.33%) fetuses agreed to be induced and 84 (56.00%) were normal. Ultrasound diagnosis results and induction of labor or fetal birth are basically the same. The ultrasound screening sensitivity was 87.33% (131/151), the specificity was 100.00% (150/150), the positive predictive value was 100.00% (150/150). Conclusion Early fetal ultrasound screening of fetuses with high-risk pregnancies is of great importance in the prevention of adverse pregnancy outcomes.