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作者用真丝微粒制作多发性脑梗塞模型。颈内动脉推注微粒后,同侧脑电图显示出快波活动减少和波幅降低。对侧肢体出现不同程度的瘫痪。不同时间杀死的大鼠,用两种染色法进行病灶面积比较,发现早期杀死动物TTC染色病灶面积较HE染色的病灶面积小。后期两种染色无差别。对有肢体瘫痪鼠的皮层及基底节区梗塞面积进行比较,认为基底节区梗塞的大小对肢体瘫痪的影响较大P<0.0025。这可能是基底节区纤维较集中所致。
The author uses silk particles to make a model of multiple cerebral infarction. After injection of particles into the internal carotid artery, ipsilateral EEG showed a decrease in fast wave activity and a decrease in amplitude. Contralateral limb paralysis of varying degrees. Rats killed at different times were compared in lesion area by two staining methods, and it was found that the area of TTC staining lesion in the early killed animals was smaller than the lesion size of HE staining. The latter two kinds of staining no difference. Comparison of cortical and basal ganglia infarction area in patients with limb paralysis suggested that the size of infarction in basal ganglia had a greater impact on limb paralysis (P <0.0025). This may be due to more concentrated basal ganglia fibers.