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40例剖胸病人分两组,Ⅰ组于术后采用硬膜外连续输注布比卡因和芬太尼复合液,Ⅱ组于术后硬膜外推注吗啡,比较两组的镇痛、镇静效果,以及镇痛前后的Bp、HR、R、VC、TV、SpO2变化和副作用。结果示:Ⅰ组比Ⅱ组镇痛作用起效快,咳嗽VRS评分高,VC增加更显著,术后增快的呼吸减慢较明显,恶心、呕吐发生率Ⅰ组为8%,Ⅱ组为26.7%。Ⅰ组无尿潴留,Ⅱ组尿潴留发生率为53,3%。
Forty patients with thoracotomy were divided into two groups. Group Ⅰ was given epidural continuous infusion of bupivacaine and fentanyl after operation. Group Ⅱ was injected epidural morphine after operation. Analgesia was compared between the two groups , Sedative effect, and changes of Bp, HR, R, VC, TV, SpO2 and side effects before and after analgesia. The results showed that the analgesic effect of group Ⅰ was faster than that of group Ⅱ. The cough score of VRS was high, the increase of VC was more significant, and the postoperative accelerated breathing was more obvious. The incidence of nausea and vomiting was 8% in group Ⅰ, 26.7%. No urinary retention in group Ⅰ, urinary retention in group Ⅱ was 53.3%.