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为了眼底荧光血管造影、吲哚菁绿血管造影(FFA.ICGA)同步激光扫描的需要,我们观察了国产荧光素钠与吲哚菁绿造影剂混合应用对血压、脉搏的影响。方法:对100例需要做FFA与ICGA同时检查的眼底病患者,并分两个年龄组:老龄组(59~76岁),中低龄组(18~58岁)。所有患者给予两种血管造影剂混合后注射,在不同时间(注射前与注射后即刻,注射后10分钟、30分钟)进行了血压和脉搏的比较。结果:经统计学处理,100例患者中及两个不同年龄组注射后即刻的收缩压、舒张压(老龄组除外)均比注射前升高(P<0.01),老龄组舒张压差异无显著性(P>0.05)。脉搏均比注射前减慢(P<0.01)。注射后10分钟、30分钟的收缩压、舒张压与注射前相比差异不显著(P>0.05),而脉搏减慢仍有显著差异(P<0.05),但仍在正常生理范围。结论:两种造影剂混合应用,对血压的影响只是一过性升高,很快可以恢复。对老年人的舒张压影响不大。脉搏较注射前减慢,持续时间较长,但在正常范围。所以,两种国产造影剂混合使用是安全的
For fundus fluorescein angiography, indocyanine green angiography (FFA.ICGA) synchronous laser scanning needs, we observed the domestic application of sodium fluorescein and indocyanine green contrast agent on blood pressure, pulse. Methods: One hundred patients with ocular fundus disease who needed simultaneous examination of FFA and ICGA were divided into two age groups: aged group (59-76 years) and middle-aged group (18-58 years). All patients were given a mixture of two angiographic contrast agents and were compared for blood pressure and pulse at different times (before and after injection, 10 minutes and 30 minutes after injection). Results: After statistical treatment, the systolic and diastolic blood pressure (except for the old group) in 100 patients and two different age groups immediately after injection increased compared with that before injection (P <0.01), and the difference in diastolic blood pressure No significant (P> 0.05). The pulse rate was slower than before injection (P <0.01). Systolic blood pressure and diastolic blood pressure at 10 minutes and 30 minutes after injection were not significantly different from those before injection (P> 0.05), but there was still significant difference between the two groups (P <0.05) range. Conclusion: The combination of two contrast agents, the impact on blood pressure is only transiently elevated, and can be quickly restored. Little effect on diastolic blood pressure in the elderly. Pulse slower than before injection, longer duration, but in the normal range. Therefore, the two home-made contrast agent mixed use is safe