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目的探讨细胞间粘附分子-1(ICAM-1)和血管细胞间粘附分子-1(VCAM-1)在急性白血病(AL)中的表达及临床意义。方法 39例初诊 AL 患者中急性淋巴细胞白血病(ALL)12例,急性非淋巴细胞白血病(ANLL)27例,其中27例达完全缓解(CR)。采用逆转录-PCR(RT-PCR)法检测 AL 骨髓单个核细胞 ICAM-1和 VCAM-1的
Objective To investigate the expression and clinical significance of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) in acute leukemia (AL). Methods Thirty - nine patients with acute lymphoblastic leukemia (ALL) were enrolled in this study. Twenty - seven cases were acute lymphoblastic leukemia (ALL) and 27 cases were acute non - lymphocytic leukemia (ANLL). Among them, 27 cases achieved complete remission (CR). Reverse transcription-PCR (RT-PCR) was used to detect ICAM-1 and VCAM-1 in AL bone marrow mononuclear cells