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目的:探讨发生双侧乳腺癌的相关因素和对预后的影响。方法:观察17例女性双侧原发乳腺癌的发生时间、年龄、月经、肿瘤细胞类型、手术方式与生存质量的关系。结果:发病年龄呈现年轻化趋势,尤其同时性双侧乳腺癌明显,绝经前女性更易发生双侧乳腺癌;双侧乳腺癌的发生与病理类型无关,未发现有乳腺癌家族史。结论:加强一侧乳腺癌术后患者尤其年轻和绝经前女性的随诊,不仅要注意有无复发转移,而且要注意健侧乳腺有无癌变。
Objective: To investigate the related factors of bilateral breast cancer and the impact on prognosis. Methods: The relationship between the occurrence time, age, menstruation, tumor cell type, operation method and quality of life of 17 cases of bilateral primary breast cancer were observed. Results: The age of onset showed a trend of younger age, especially in bilateral breast cancer. Premenopausal women were more likely to develop bilateral breast cancer. The incidence of bilateral breast cancer was not related to the pathological type, and no family history of breast cancer was found. Conclusion: To strengthen the postoperative patients with breast cancer especially young and premenopausal women follow-up, not only to pay attention to recurrence and metastasis, but also pay attention to whether the contralateral breast cancer.