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作者报告一个有30个成员的家系,其中4个发生白血病。他(她)们的遗传标志,包括HLA抗原、血清蛋白和红细胞酶的多形性(Polymorphism)及皮肤成纤维细胞的细胞遗传学研究已另文报导,本文重点报告有关白血病素质的遗传资料。白血病病例资料:4例病儿均为同辈,其中2男1女为同胞兄妹,另一例为远亲。临床特征均相似,4例发病均在4岁以下,都为急性淋巴细胞白血病(ALL),都有不同程度的肝脾大。作过免疫分型的两例均为非T非B型,其末端脱氧核苷转移酶活性均
The authors report a family of 30 members, of whom 4 developed leukemia. He and her genetic markers, including HLA antigens, serum protein and erythrocytic enzyme polymorphisms (Polymorphism) and skin fibroblasts in cytogenetics have been reported in another article, this article focuses on the genetic material on the quality of leukemia. Leukemia Case Information: 4 cases of sick children are of the same generation, of which 2 men and 1 woman siblings siblings, and the other is distant relatives. Clinical features are similar, 4 cases were less than 4 years of age, all acute lymphoblastic leukemia (ALL), have varying degrees of hepatosplenomegaly. Two of the immunotypes were non-T non-B type, the terminal deoxynucleotidyl transferase activity were