恶性肿瘤併发自身免疫性溶血性贫血较为少见,其意义不明。文献报告中大多数是卵巢肿瘤,上皮细胞癌很少。皮质激素、脾切除治疗这种贫血都不能奏效,只有在切除原发癌肿后,溶血性贫血才能得到纠正。作者报告一男性病人,42岁,以溶血性贫血起病,Goombs试验直接阳性,抗体属于IgG型。进一步检查洗脱的自身抗体,鉴定抗体为抗c(红细胞表型为cc dd ee)。其他抗体如抗核、抗核蛋白、抗 Malignant tumors complicated by autoimmune hemolytic anemia is rare, its meaning is unknown. Most reports in the literature are ovarian tumors, epithelial cell carcinoma is very small. Corticosteroids, splenectomy treatment of such anemia can not be effective, only after removal of the primary cancer, hemolytic anemia can be corrected. The authors report a male patient, 42 years old, who developed hemolytic anemia. The Goombs test is directly positive and the antibody is of the IgG type. Eluted autoantibodies were further examined and antibodies identified as anti-c (erythrocytic phenotype cc dd ee). Other antibodies such as anti-nuclear, anti-nuclear protein, anti-