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目的探讨左心室扩大患者可能的临床危险因素。方法冠状动脉造影(CAG)患者96例,46例诊断左心室扩大(A组),50例左心室正常(B组)。观测项目:血糖(BG),总胆固醇(TC),高密度脂蛋白胆固醇(HDL-C),低密度脂蛋白胆固醇(LDL-C),甘油三酯(TG),尿酸(UA),白细胞(WBC),高敏C反应蛋白(hs-CRP),ST段压低程度(STD),冠脉前降支血流时间(LADET),左心室舒张末内径(LVDD),左心射血分数(LVEF)值。结果 A组2型糖尿病(T2DM)患者比例高于B组(69.6%vs.28.0%)(P<0.01)。A组高血压患者比例高于B组(76.1%vs.54.0%)(P<0.05)。A组年龄、WBC、UA、BG、hs-CRP、STD、LADET、EF、LVDD均显著高于B组(P<0.01)。Linear回归分析显示,T2DM、年龄、LADET是左心室扩大的独立危险因素(P<0.05或P<0.01)。结论T2DM、年龄、LADET是左心室扩大的独立危险因素。
Objective To investigate the possible clinical risk factors in patients with left ventricular enlargement. Methods 96 cases of coronary angiography (CAG), 46 cases of diagnosis of left ventricular enlargement (A group), 50 cases of left ventricular normal (B group). Observation items: Blood glucose (BG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), triglyceride (TG), uric acid (UA) WBC, hs-CRP, ST-segment depression, LADET, LVDD, LVEF, value. Results The proportion of patients with type 2 diabetes mellitus (T2DM) in group A was higher than that in group B (69.6% vs.28.0%) (P <0.01). The proportion of patients with hypertension in group A was higher than that in group B (76.1% vs.54.0%) (P <0.05). The age, WBC, UA, BG, hs-CRP, STD, LADET, EF and LVDD in group A were significantly higher than those in group B (P <0.01). Linear regression analysis showed that T2DM, age, and LADET were independent risk factors for left ventricular enlargement (P <0.05 or P <0.01). Conclusion T2DM, age, LADET are independent risk factors of left ventricular enlargement.