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本文以巨细胞病毒(CMV)核酸杂交技术检测34例婴儿肝炎综合征患者尿标本的带病毒水平。结果表明其感染率(44.1％)明显高于正常对照组(15％,P<0.05)。并初步发现CMV感染在患者母婴间分布有较高的相关性(符合率为13/14)。对患者体液免疫分析的结果表明,伴发CMV感染的婴儿肝炎病理过程不涉及类似Ⅲ型变态反应的免疫病理变化,但其血清C_3水平明显低下,原因值得进一步探讨。
In this paper, cytomegalovirus (CMV) nucleic acid hybridization detection of 34 cases of infantile hepatitis syndrome in patients with urine samples of the virus level. The results showed that the infection rate (44.1%) was significantly higher than the normal control group (15%, P <0.05). And initially found that the distribution of CMV infection in patients with high correlation between maternal and infant (with a rate of 13/14). The results of humoral immunoassay showed that the pathological process of infantile hepatitis with CMV infection did not involve the immunopathological changes similar to type Ⅲ allergic reaction, but the serum C_3 level was significantly lower, the reason worth further exploration.