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目的分析江苏省186例急性弛缓性麻痹(AFP)病例残留麻痹的流行特征及其相关影响因素,寻找早期预防措施。方法对2004-2009年江苏省残留麻痹的AFP病例的186例流行特征进行描述流行病学分析,对相关影响因素进行单因素和多因素非条件Logistic回归分析。结果江苏省2004-2009年AFP病例残留麻痹率为12.02%,2007-2009年残留麻痹率较2004-2006年下降50.46%;宿迁县和徐州市AFP残留麻痹率高于全省平均水平;186例残留麻痹AFP病例中,男性多于女性,每年4-7月发病数较多,65.59%的病例集中在0~4岁儿童;多因素非条件Logistic回归分析显示,年龄、性别、免疫史、粪便标本实验室结果、初始麻痹程度、粪便标本质量和AFP报告单位级别等与AFP病例残留麻痹的发生有关联。结论将乡镇卫生机构纳入AFP主动监测医院范围,提高监测系统敏感性、脊灰疫苗接种率和儿童就诊及时率,是降低AFP病例残留麻痹率的有效措施。
Objective To analyze the epidemiological characteristics and related factors of residual paralysis in 186 cases of acute flaccid paralysis (AFP) in Jiangsu Province and to find out the early preventive measures. Methods Epidemiological characteristics of 186 cases of AFP cases with residual paralysis in Jiangsu Province from 2004 to 2009 were described. Univariate and multivariate non-conditional Logistic regression analysis was performed on the related factors. Results Residual paralysis rate of AFP cases in Jiangsu province during 2004-2009 was 12.02%. The residual paralysis rate in 2007-2009 was 50.46% lower than that in 2004-2006. The residual paralysis rate of AFP in Suqian County and Xuzhou City was higher than the provincial average level. 186 cases Residual paralysis AFP cases, more men than women, the incidence of 4-7 months a year more, 65.59% of cases concentrated in children aged 0-4 years; multivariate non-conditional Logistic regression analysis showed that age, gender, history of immunization, faeces Specimen laboratory results, initial paralysis, stool specimen quality and AFP reporting unit level and other cases of AFP residual paralysis associated with the occurrence. Conclusion It is an effective measure to reduce the residual paralysis rate of AFP cases by including township health institutions in AFP to monitor the hospital voluntarily, and improve the sensitivity of monitoring system, polio vaccination rate and timely treatment of children.