妊娠滋养细胞疾病(gestationaltrophoblasticdisease,GTD)是一组起源于胎盘绒毛滋养细胞的疾病,主要包括葡萄胎、侵袭性葡萄胎和绒毛膜癌,后二者又称为恶性滋养细胞肿瘤。妊娠滋养细胞疾病病因和发病机制尚不清楚。一般认为葡萄胎为良性病变,但它有潜在恶变的倾向,可恶变为侵袭 Gestational gestational trophoblastic disease (gestational trophoblastic disease, GTD) is a group of placental villi trophoblast disease, including hydatidiform mole, invasive hydatidiform mole and choriocarcinoma, the latter two are also known as malignant trophoblastic tumor. The etiology and pathogenesis of gestational trophoblastic disease is not clear. It is generally believed that hydatidiform mole is a benign lesion, but it has the potential of malignant transformation, malignant change into invasion