在第三讲中我们叙述了给药方案的拟订原理,并指出:一种药物的常规剂量方案,必要时应根据病人个体的特点或药物的体内动力学特性的不同,进行适当的调整。上一讲讨论了老年人的合理用药问题,本讲则简述在儿童、肾功能不全病人以及呈非线性药物动力学特性等特殊情况下剂量方案的拟订或调整,作为整个讲座的结束。 In the third lecture, we describe the formulation principles of the dosing regimen and point out that the usual dosing regimen of a drug, if necessary, should be tailored to individual patient characteristics or the pharmacokinetic properties of the drug. The previous talk discussed the issue of rational drug use in older adults. This talk briefly outlines the formulation or adjustment of dosage regimens in special cases such as children, patients with renal insufficiency, and non-linear pharmacokinetic characteristics as the concluding lecture.