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目的通过对非结核分枝杆菌(NTM)肺病病例的回顾性分析,探讨非结核分枝杆菌肺病的临床特征。方法对本院2005年1月~2008年10月住院34例非结核分枝杆菌肺病的临床资料进行回顾分析。结果363例分支杆菌培养检出34例非结核分枝杆菌,检出率为9.37%,临床特征有咳嗽、咳痰34例(100%),消瘦17例(50%),气促12例(35.3%),咯血11例(32.4%),胸膜炎8例(23.5%),乏力6例(17.6%),发热4例(11.8%),盗汗3例(8.8%);痰涂片抗酸杆菌阳性8例(23.5%)。胸部影像学:3个肺野23例(67.6%),其中两侧全肺野10例(29.4%),空洞12例(35.3%)。耐药情况:34例患者的耐药率为100.0%,其中异烟肼(INH)最高28例(82.4%)。结论非结核分枝杆菌肺病临床表现与肺结核相似,肺部病灶以多肺野为主,两上肺空洞多见,进展缓慢,耐药率高。
Objective To investigate the clinical characteristics of non-tuberculosis mycobacterium tuberculosis by retrospective analysis of non-tuberculosis (NTM) lung disease cases. Methods The clinical data of 34 cases of non-tuberculous mycobacterium tuberculosis hospitalized in our hospital from January 2005 to October 2008 were retrospectively analyzed. Results 363 cases of Mycobacterium tuberculosis were detected in 34 cases of non-tuberculous mycobacteria detection rate was 9.37%, the clinical features of cough, sputum in 34 cases (100%), weight loss in 17 cases (50%), shortness of breath in 12 cases 35.3%), hemoptysis in 11 cases (32.4%), pleuritis in 8 cases (23.5%), fatigue in 6 cases (17.6%), fever in 4 cases (11.8%) and night sweats in 3 cases (8.8% Positive in 8 cases (23.5%). Chest imaging: 23 cases of lung field in 23 cases (67.6%), including the two sides of the lung field in 10 cases (29.4%), empty in 12 cases (35.3%). Drug resistance: drug resistance in 34 patients was 100.0%, of which isoniazid (INH) up to 28 cases (82.4%). Conclusions The clinical manifestations of non-tuberculous mycobacterium tuberculosis are similar to those of pulmonary tuberculosis. The lung lesions are dominated by multiple lung fields. The two lung cavities are common and progress slowly with high drug resistance rate.