[目的 ]分析、探讨职业性慢性正己烷中毒的临床表现、诊断以及防治。 [方法 ]对我院收治的 4例职业性慢性正己烷中毒病例进行分析。[结果 ]慢性正己烷中毒的临床表现主要有不同程度的感觉、运动障碍 ,表现为肢端麻木、肌无力 ,肌电图呈神经源性损害 ,严重的可进行性加剧 ,出现肌萎缩 ;治疗上主要使用神经生长因子和各种神经营养药 ,但症状恢复较慢。 [结论 ]正己烷虽属低毒类 ,但长期接触可致以周围神经损害为主的慢性中毒 ,影响工作和生活能力 ,因此要加强正己烷中毒的防治 [Objective] To analyze and discuss the clinical manifestation, diagnosis and prevention of occupational chronic n-hexane poisoning. [Methods] Four cases of occupational chronic n-hexane poisoning in our hospital were analyzed. [Results] The clinical manifestations of chronic n-hexane poisoning mainly have different degrees of sensory and motor dysfunction, manifested as extremity numbness, muscle weakness, electromyogram neurogenic damage, severe progressive worsening, muscle atrophy; treatment On the main use of nerve growth factor and a variety of neurotrophic drugs, but the symptoms recover more slowly. [Conclusion] Although n-hexane is a kind of low-toxic, long-term exposure can lead to chronic poisoning of peripheral nerve damage, affecting the working and living ability, therefore, we should strengthen the prevention and control of n-hexane poisoning