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目的探讨免疫因素在蛛网膜下腔出血后迟发性脑血管痉挛的发生机制中的作用。方法采用兔复制动物模型，经颅多普勒监测血管痉挛发生情况，实验前后检测外周血IL－2活性。结果实验组动物迟发性脑血管痉挛的发生率达84．62％；实验第7天实验组外周血中IL－2活性较实验前显著增高（P＜0．01）。结论在蛛网膜下腔出血后迟发性脑血管痉挛的发生机制中确有免疫因素的参与。
Objective To investigate the role of immune factors in the pathogenesis of delayed cerebral vasospasm after subarachnoid hemorrhage. Methods Rabbit replicate animal models were used to detect the occurrence of vasospasm by transcranial Doppler. The levels of IL-2 in peripheral blood were measured before and after the experiment. Results The incidence of delayed cerebral vasospasm in experimental group was 84.62%. On the 7th day, the activity of IL-2 in experimental group was significantly higher than that before experiment (P <0.01). Conclusion There are indeed immune factors involved in the pathogenesis of delayed cerebral vasospasm after subarachnoid hemorrhage.